I just got done setting up automatic backups to Rackspace Cloud files for a MySQL db running on Centos 5.4. I followed this guide here which is directed at Ubuntu 9.10 users, but worked just fine on Centos. Only change I really had to make was installing via yum, as opposed to apt-get.
It went pretty smoothly, and my db is now being backed up once every hour, on the hour to my cloud files container. Sweet stuff.
I won’t regurgitate the code, so just visit this URL to get educated: (just remember to pick up the latest version of python-cloudfiles, because the link in the article is a couple releases behind).